Dead Cells Guide - Tips and Tricks, How to Get Every Rune, Secrets (2024)

Everything you need to get started in Dead Cells.

Dead Cells Guide - Tips and Tricks, How to Get Every Rune, Secrets (2)

Guide by Jake Green Contributor

Updated on

Dead Cells sees players controlling a parasite which has overwhelmed the body of a dead prisoner. The gameplay is just as mad, offering up souls-like combat punctuated by loot and map-unlocking upgrades. it is a difficult game from the outset, so having a few key bits of info fresh in your mind will be a real advantage. Luckily, we've pulled together this Dead Cells Tips Guide. It's got details on where Runes are, what they do, as well as general tips and tricks to help you stay alive.

We’ll be adding more to this guide as we spend more time with the game so be sure to check back regularly. If there’s anything you’d like any help with in the game, let us know in the comments below.

Dead Cells Guide

Dead Cells combines elements of roguelikes and Metroidvania. It tasks players with controlling a dead prisoner, re-animated by a mass of powerful cells. It’s your classic Metroidvania fare, as players collect weapons and upgrades which allow them to access previously inaccessible areas of the map. Dead Cells is meant to be challenging, garnering comparisons to the Souls series where combat is concerned.

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Dead Cells Tips and Tricks

Dead Cells is designed to be an incredibly tough game. But while the combat is tough to get your head around at first, there are some general tips that you should keep in mind as you play. Here are some Dead Cells Tips and Tricks to help you survive:

  • Treat every enemy like you would a boss - Even common enemies can kill you easily if you’re not careful.
  • Use doors as battering rams - You can rush through doors to slam them into enemies, stunning them in the process.
  • Roll - Use the roll to get behind enemies after they’ve attacked, you can do huge damage this way.
  • The skills stat kinda sucks - The skills stat is by far the worst one to invest levelling up in.
  • Stomp! - Hold down and jump while in the air and you’ll perform a stomp. This can be used to dodge, or as an attack.
  • Don’t be afraid to run - Just like in Dark Souls, sometimes running to the next area is the best option you will have.
  • Early on, focus on Blueprints and Runes - You won’t get all that far without good weapons and Runes to get you through.
  • Experiment with builds - there are a lot of different play styles that you can go with in Dead Cells, be open minded and try them out.
  • Never stop moving - There are timed doors in some areas which will trigger as you enter, keep moving and you’ll always be prepared to beat them. They offer great rewards, so worth pursuing.
  • The Shield is your friend - make use of the game’s parry function, it can negate damage and stun enemies if done correctly.
  • early on, focus on the more general upgrades like health and gold, this will allow you to survive for longer, and make each run more lucrative. It also means that you can spend a little time with the combat system before wasting upgrades on elements you are not going to use after a while.
  • At present, Dead Cells on Switch can be a little framey when undocked. Keep this in mind when playing.
  • Enemies will get more powerful the more scrolls you find. Certain members of the community are suggesting that you actually stop collecting them early on, as the damage you'll take will be super low.
Dead Cells Guide - Tips and Tricks, How to Get Every Rune, Secrets (4)

Dead Cells Runes - How to Get Every Rune

Runes are incredibly important in Dead Cells. They unlock permanent upgrades that you will need in order to fight harder enemies. Runes grant everything from wall running to being able to smash through weak floors. Here’s how to get every Rune in Dead Cells:

Dead Cells Vine Rune

The Vine Rune unlocks the ability to sprout vines from green blobs located around the map, here’s how to get it:

  • In the Promenade of the Condemned.
  • Look for a door found at the base of a large overhang.
  • Defeat the Undead Archer
  • Claim the Rune

Dead Cells Teleportation Rune

The Teleportation Rune unlocks the ability to teleport between pairs of coffins, here’s how to get it:

  • Head to the Toxic Sewers, you’ll need the Vine Rune to get there
  • Look for a switch-operated door
  • There’s a room beneath it
  • Defeat the slasher
  • Collect the Rune

Dead Cells Belier Rune

The Belier Rune or Ram Rune allows you to break weak floors marked with a yellow sign. Here’s how to get ahold of it:

  • Head to the Ossuary
  • Find a door that can only be opened by breaking the fragile ground above a button
  • The Rune is in that room
  • Defeat the Elite Slasher

Dead Cells Challenger Rune

The Challenger Rune is massively useful in Dead Cells. It opens the daily run door in the Prisoner’s Cells.

  • To get the Challenger Rune, head to The Black Bridge
  • Defeat the Incomplete one
  • Collect the Rune

Dead Cells Spider Rune

The Spider Rune let’s you stick to walls, and is needed to access certain areas, here’s how to get it:

  • Defeat the Elite Orb Caster located in the Slumbering Sanctuary
  • To get there, head through the Insufferable Crypt, and clear the Watcher boss fight
  • Collect the Spider Rune
Dead Cells Guide - Tips and Tricks, How to Get Every Rune, Secrets (5)

How to Find Secrets in Dead Cells - Hidden Challenge Portals

There are plenty of secrets to find in Dead Cells, though you’d be forgiven for not knowing where to look. Well, secrets in Dead Cells are actually located by finding single squares in the environment that have a faint blue glow to them. Breaking these blocks will give you Gold or Food, so they’re definitely worth keeping an eye out for. They can also summon hidden portals when broken, if they are under the ground that is. These hidden portals will transport you to Challenge Areas.

That’s all of our tips on getting started in Dead Cells. The key thing to keep in mind is that you are supposed to die, a lot. Just keep pushing towards new blueprints and Runes and you’ll start to gain the upperhand.

Dead Cells Guide - Tips and Tricks, How to Get Every Rune, Secrets (2024)

FAQs

How to get every rune in dead cell? ›

All runes will drop after the guardian is defeated and can be picked up afterwards, save for the Homunculus rune, which is acquired automatically after the Hand of the King is defeated.

What's the best weapon in Dead Cells? ›

The Barnacle Turret breaks the mold by being arguably the strongest autonomous weapon in Dead Cells with its ability to fire poisonous barbs at targets. While you can only have one at a time, enemies cannot target the device, even though it can still be destroyed.

What are the secret walls in Dead Cells? ›

Wall secrets are breakable tiles hidden within the walls or the ground of each zone which glow when the player is in close proximity. Breaking a wall secret will spawn a food item or a random gem.

Should you unlock every weapon in Dead Cells? ›

depends on how you look at it, its good if you want a bigger armory, but it's bad because those other weapons will be spawning (at the start) in placement of the weapons you really want.

How to get Ram rune? ›

Where do you find the Ram Rune? In the Ossuary. This is an area that can be accessed from the Promenade of the Condemned. If you go all the way to the end of the Promenade, you'll find the elevator leading up to the Ramparts.

What is the secret sword in Dead Cells? ›

Summons a flying sword that will mark enemies, trigger it again to inflict critical hits on them while holding the weapon, and vice-versa! The sword will vanish after 30 sec if you don't hit the marked enemies.

How do you get the secret outfit in Dead Cells? ›

They are unlocked by finding their blueprints and unlocking them from the Collector with cells like all other upgrades or items. Once at least one new outfit is unlocked from the Collector, the player can change outfits by entering the Tailor's shop at the start of Prisoners' Quarters.

How do you unlock Alucard Dead Cells? ›

Alucard can be found sleeping in a coffin in the Castle's Outskirts. The player can awaken him be knocking on the coffin.

What is the strongest build in Dead Cells? ›

These are just a few of the reasons why Tactics builds are so powerful. As you can see, Tactics is clearly the strongest build in Dead Cells. What is your favorite build and why is it Tactics?

How to unlock Alucard sword? ›

Notes[edit]
  1. This weapon is unlocked by finding Alucard in Richter Mode.
  2. Attacks performed after teleporting will have windup of 0.15s instead of 0.33s. These faster attacks are technically counted as separate from their slower versions, comprising the fifth through eighth hits of the 8 attack combo.
Jun 22, 2024

How do you unlock secret blueprints in Dead Cells? ›

When a blueprint is found, the player has to talk to the Collector in any biome transition to deliver it and be able to unlock it. They can be unlocked by paying cells for them at the Collector.

What is the magic mirror for in Dead Cells? ›

The Hunter's Mirror is an upgrade offered by the Collector. When unlocked, a mirror appears at the start of the Prisoners' Quarters, next to the Scribe. When interacted with, it shows a random enemy or boss that carries a blueprint not currently acquired.

What are the doors you knock on in Dead Cells? ›

Door can designate to three things in Dead Cells: Timed and Perfect Doors, transition level doors found in Passages that contain cells, gems, and items. BSC Doors, bonus doors scattered through the levels that are locked behind a particular BSC difficulty.

How do you get custom rune Dead Cells? ›

Customization Rune, obtained from killing a unique Elite Zombie at the start of Ramparts, but some configurations are available only by beating the game at harder difficulties. . This mode only allows using items that have been unlocked through the Collector in Normal Mode.

How do you unlock abyssal Trident Dead Cells? ›

Location[edit] Forked Key which unlocks the lore room. Inside the room is a pedestal containing the Trident. When picked up it unlocks it permanently and drops a legendary version of the weapon.

How many runes do you get for killing bosses? ›

Tips
BossNG Runes
Soldier of Godrick400
Beastman of Farum Azula1000
Mad Pumpkin Head (Waypoint Ruins)1100
Black Knife Assassin (Dt. Catacombs)1600
88 more rows

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