Mutations (2024)

Perks are passive items that modify and increase the abilities of the player in various ways. They are obtained between levels from Tutorial Knight. Most are not initially available, so in order to unlock them, one must bring their blueprints to the The Boy's Axe, then spend the required cells.

Contents

  • 1 Mechanics
  • 2 List of mutations
    • 2.1 List of Brutality Perks
    • 2.2 List of Tactics mutations
    • 2.3 List of Survival mutations
    • 2.4 List of Colorless mutations
  • 3 Removed mutations
  • 4 History

Mechanics[]

The player can only have a amount of Perks at once. Each area cleared in a run allows one more mutation, up to a total of 11 (unless in custom mode, where many more can be picked). However, the player can spend gold between levels to remove all current mutations, allowing a new choice of mutations to replace the old set. The price to do this starts at 1,000 and doubles with each reset, until the cost reaches 8,000 gold, at which point it will stop increasing.

Most Perks are associated with and scale their benefits with a specific stat. That is, Perks' base damage and/or healing magnitudes are multiplied by 1.15n-1, where n is the current level of the appropriate stat, rounded to produce the final amount.

For example, if a Brutality Perks provides an extra 90 base DPS and the player's Brutality is 2, the final extra DPS is 90 × 1.152-1 = 90 × 1.15 = 103.5 ≈ 104). Note that damage and DPS bonuses from mutations are not affected by gear-specific damage bonuses or Affixes.

Colored Perks have fixed benefits unaffected by Stats, except for Instinct of the Master of Arms and Frostbite which scale on the highest stat.

List of mutations[]

There are 54 mutations in the game: 12 for Brutality, 12 for Tactics, 12 for Survival and 17 that are Colorless.

List of Brutality Perks[]

IconNameDescriptionLocationCell cost Mutations (1)

Mutations (2)

[[{{{_pageName}}}|Killer Instinct]]Reduces the cooldown of your skills by [0.4 base, 3 max] seconds for each enemy killed in hand to hand combat.Always availableN/A

Mutations (3)

[[{{{_pageName}}}|Combo]]+[15% base] damage for 8 seconds after killing an enemy.Always availableN/A

Mutations (4)

[[{{{_pageName}}}|Vengeance]]+[60% base] damage dealt for 8 seconds and -30% damage taken for 3 seconds after taking damage.Always availableN/A

Mutations (5)

[[{{{_pageName}}}|Melee]]Melee attacks slow down enemies for [0.2 base, 0.8 max] seconds.The Concierge (5th kill)50

Mutations (6)

[[{{{_pageName}}}|Open Wounds]]Melee attacks inflict bleeding ([18 base] DPS for 1.5 seconds)Lacerators (0.4%)50

Mutations (7)

[[{{{_pageName}}}|Tainted Flask]]Using a health flask adds +[20% base] damage to your attacks for 12 sec. If have your mother, no empty flask charged remainingThe Time Keeper (6th kill)50

Mutations (8)

Tainted FlaskUsing a health flask adds +[20% base] damage to your attacks for 12 sec. If no flasks are left, killing 12 elite enemies will refill one flask.The Time Keeper (6th kill)50

Mutations (9)

[[{{{_pageName}}}|Adrenaline]]Melee attacks restore a small amount of HP depending on attack damage for 5 sec after dodging an attack at the last moment.Rampagers (3+ BSC; 1.7%)100

Mutations (10)

[[{{{_pageName}}}|Frenzy]]Melee attacks restore a small amount of HP depending on attack damage as long as you have an active speed buff.Timed door in the Passage before Toxic Sewers50

Mutations (11)

[[{{{_pageName}}}|Scheme]]Your next melee attack after using a skill inflicts +[200 base] damage.Sweepers (10%)50

Mutations (12)

[[{{{_pageName}}}|Initiative]]Your first melee strike against an enemy inflicts +[100 base] damage.Royal Guards (10%)50

Mutations (13)

[[{{{_pageName}}}|Predator]]Killing an enemy with a melee strike makes you invisible for [1 base, 3.5 max] seconds.Automatons (10%)50

Mutations (14)

[[{{{_pageName}}}|Porcupack]]Rolling through enemies attacks them with the melee weapon in backpack for [75% base] of the usual damages.Rancid Rats (0.4%)80

List of Tactics mutations[]

IconNameDescriptionLocationCell cost Mutations (15)

Mutations (16)

[[{{{_pageName}}}|Support]]+[10% base] damage if you're close to a deployed skill.Always availableN/A

Mutations (17)

[[{{{_pageName}}}|Parting Gift]]Causes a bomb ([75 base] damage) to appear when you kill an enemy with a non-melee attack.Secret area in Graveyard100

Mutations (18)

[[{{{_pageName}}}|Tranquility]]+[25% base] damage if there are no enemies near you.Always availableN/A

Mutations (19)

[[{{{_pageName}}}|Ripper]]Hand to hand attacks cause 6 arrows stuck in the attacked enemy to fall out, each one dealing [118 base] damage.Secret area in Promenade of the Condemned100

Mutations (20)

[[{{{_pageName}}}|Ranger's Gear]]Your next ranged attack after using a skill inflicts [180 base] damage.Dancers (10%)50

Mutations (21)

[[{{{_pageName}}}|Barbed Tips]]Inflicts [40 base] dps per arrow stuck to enemies.Toxic Miasmas (10%)80

Mutations (22)

[[{{{_pageName}}}|Point Blank]]Close-ranged ranged attacks inflicts [30 base]% bonus damage.Corpulent Zombies (10%)80

Mutations (23)

[[{{{_pageName}}}|Networking]]Enemies with arrows stuck in them share [35% base, 75% max] of the damage they receive.Swarm Zombies (10%)50

Mutations (24)

[[{{{_pageName}}}|Crow's Foot]]Rolling leaves 3 crow's feet behind you (with a maximum of 9), inflicting [50 base] damage and slowing the enemies for 1.5 seconds.Inside a chest in a Challenge Rift50

Mutations (25)

[[{{{_pageName}}}|Tactical Retreat]]Dodging an attack at the last moment slows down nearby enemies for [1 base, 3 max] seconds.Slammers (10%)100

Mutations (26)

[[{{{_pageName}}}|Hunter's Instinct]]Decreases skill cooldowns by [0.3 base, 2.5 max] seconds for each enemy killed with using ranged attacks.Always availableN/A

Mutations (27)

[[{{{_pageName}}}|Acrobatipack]]Attacking with a ranged weapon, after rolling with a ranged weapon in your backpack fires a projectile of said weapon, dealing [25% base] of the usual damages.Demolishers (10%)120

List of Survival mutations[]

IconNameDescriptionLocationCell cost Mutations (28)

Mutations (29)

[[{{{_pageName}}}|Soldier's Resistance]]Increases your health by [7% base. 40% max].Guardian Knights (1.7%)100

Mutations (30)

[[{{{_pageName}}}|Berserker]]Killing an enemy with a melee attack reduces the damage you take by [10% base, 60% max] for 5 sec. Can stack up to 90%. Also makes you immune to stuns.Failed Experiments (4+ BSC; 0.4%)100

Mutations (31)

[[{{{_pageName}}}|Blind Faith]]Reduces the cooldown on your skills by [2.8 base, 6 max] seconds with each successful parry.Always availableN/A

Mutations (32)

[[{{{_pageName}}}|Counterattack]]The attack following a successful parry inflicts +[210 base] damage.Always availableN/A

Mutations (33)

[[{{{_pageName}}}|What Doesn't Kill Me]]Recover [2% base, 6% max] HP after parrying a melee attack.Disgusting Worms (100%)50

Mutations (34)

[[{{{_pageName}}}|Necromancy]]Recover [0.3% base, 2.5% max] HP after killing an enemy, up to a maximum of 50% HP.Always availableN/A

Mutations (35)

[[{{{_pageName}}}|Extended Healing]]Your health flask heals 85%, its effect is spread over 10 seconds and you deal +[25% base] damage during this time.Secret area in Ossuary100

Mutations (36)

[[{{{_pageName}}}|Gastronomy]]The effect of food increases by +65%. If you recycle food you deal +[10% base] damage for 300 seconds.Conjunctivius (4th kill)50

Mutations (37)

[[{{{_pageName}}}|Spite]]Successful parries and reflected shots inflict [140 base] damage.Secret area in Passage to Toxic Sewers100

Mutations (38)

[[{{{_pageName}}}|Heart of Ice]]Attacking a slowed, stunned, frozen, or rooted enemy at close range reduces skill cooldowns by [0.6 base, 2 max] seconds. Works with both melee and ranged weapons.Pirate Captains (10%)50

Mutations (39)

[[{{{_pageName}}}|Kill Rhythm]]Alternate weapons to increase your attack speed by [15% base] in 2 seconds.Oven Knights (2+ BSC; 0.4%)150

Mutations (40)

[[{{{_pageName}}}|Armadillopack]]Rolling also parries attack and projectiles with the shield in your backpack, for [50% base] of the usual damages.Thornies (1.7%)100

List of Colorless mutations[]

IconNameDescriptionLocationCell cost Mutations (41)

Mutations (42)

Mutations (43)

[[{{{_pageName}}}|Ygdar Orus Li Ox]]Saves you ONE TIME if you die prematurely while not cursed. Cannot be picked up after first mutation selection. Cannot be dropped once picked up, even if used.Always availableN/A

Mutations (44)

[[{{{_pageName}}}|Recovery]]Time available to recover your health after a hit is multiplied by 3.Conjunctivius (5th kill)50

Mutations (45)

[[{{{_pageName}}}|Emergency Triage]]Health potions only restore 35% HP but their use speed is increased by 275% and it completely protects you for 1.5 sec.The Time Keeper (7th kill)100

Mutations (46)

[[{{{_pageName}}}|Velocity]]Running speed duration bonus (for kill combo) multiplied by 3.The Time Keeper (5th kill)50

Mutations (47)

[[{{{_pageName}}}|Dead Inside]]HP is increased by 50%, but the efficiency of all sources of healing (food, mutations or health potions) is cut in half.Lancers (4+ BSC; 1.7%)100

Mutations (48)

[[{{{_pageName}}}|Alienation]]Reducing a curse restores 5% HP but increases the number of enemies required to lift the curse by 50%.The Concierge (7th kill)50

Mutations (49)

[[{{{_pageName}}}|Acceptance]]Amount of kills required to remove a curse is reduced by 50%, but consuming food curses you.Secret area in High Peak Castle200

Mutations (50)

[[{{{_pageName}}}|masoch*st]]Trap damage is capped at 10% of your max HP. When hit by a trap your movement speed increases by 20% for 20 sec.Secret area in Slumbering Sanctuary100

Mutations (51)

[[{{{_pageName}}}|Disengagement]]Once per biome, if your HP falls below 15%, a force field protects you for 5 sec.Secret area in Prisoners' Quarters200

Mutations (52)

[[{{{_pageName}}}|No Mercy]]Execute mobs under 15% health. Effect halved on bosses.Slashers (1.7%)100

Mutations (53)

[[{{{_pageName}}}|Instinct of the Master of Arms]]Reduces the cooldown on your skills by [0.08 base, 1 max] sec with each critical hit.Always availableN/A

Mutations (54)

[[{{{_pageName}}}|Ammo]]Ammo for your weapons is now 2 times what it was.The Concierge (6th kill)50

Mutations (55)

[[{{{_pageName}}}|Gold Plating]]Lose gold instead of health when hit. The gold lost is proportional to the health loss prevented.Mimics (10%)50

Mutations (56)

[[{{{_pageName}}}|Get Rich Quick]]Accumulate bonus gold for every enemy killed while you have an active speed boost and cash it in when it ends.Mimics (10%)50

Mutations (57)

[[{{{_pageName}}}|Midas' Blood]]Gain 3 gold per health points you lose.Gold Gorgers (1.7%)50

Mutations (58)

Mutations (59)

[[{{{_pageName}}}|Wish]]Turns the next item picked legendary. Cannot be removed once activated. Cannot be removed. Let's hope it was worth it.Reward for beating the 3rd Stage in Boss Rush200

Removed mutations[]

IconNameDescriptionLocationCell cost Mutations (60)Removed in

Mutations (61)

[[{{{_pageName}}}|Sadism]]+[75 base] DPS if a nearby enemy is taking poison, bleed or burn damage.Was dropped by Impaler (100%)50v1.1

Mutations (62)

[[{{{_pageName}}}|Fireworks Technician]]-[30% base, 80% max] cool down delay when using your Grenades.Always availableN/Av1.1

Mutations (63)

[[{{{_pageName}}}|Efficiency]]-[30% base, 80% max] cool down delay when using your skills.Always availableN/Av1.1

History[]

Navigation wiki
Mutations (2024)

FAQs

Mutations? ›

(myoo-TAY-shun) Any change in the DNA sequence of a cell. Mutations may be caused by mistakes during cell division, or they may be caused by exposure to DNA-damaging agents in the environment.

What are the 4 main mutations? ›

These mutations can change the location of genes on chromosomes and can even change the number of copies of some genes. There are four types of chromosomal mutations: deletion, duplication, inversion, and translocation.

What is the definition of a mutation? ›

A mutation is a change in the DNA sequence of an organism. Mutations can result from errors in DNA replication during cell division, exposure to mutagens or a viral infection.

What are examples of mutations? ›

Hereditary mutations include cystic fibrosis, hemophilia, and sickle cell disease. Other mutations can happen on their own during a person's life. These are called sporadic, spontaneous, or new mutations. They affect only some cells.

What are 5 genetic mutations? ›

Summary
  • Germline mutations occur in gametes. Somatic mutations occur in other body cells.
  • Chromosomal alterations are mutations that change chromosome structure.
  • Point mutations change a single nucleotide.
  • Frameshift mutations are additions or deletions of nucleotides that cause a shift in the reading frame.
Mar 5, 2021

What are the three 3 types of mutations? ›

There are three types of DNA Mutations: base substitutions, deletions and insertions. Single base substitutions are called point mutations, recall the point mutation Glu -----> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.

Which 3 of the following are known causes of mutations? ›

The three main factors that cause mutations are as follows:
  • Transmission of mutation from parents to children.
  • DNA repair occurs due to spontaneity in mutation.
  • The induced mutation may occur due to a chemical change or any radiation.

Is a mutation harmful? ›

Mutational effects can be beneficial, harmful, or neutral, depending on their context or location. Most non-neutral mutations are deleterious. In general, the more base pairs that are affected by a mutation, the larger the effect of the mutation, and the larger the mutation's probability of being deleterious.

What are known mutations? ›

Four classes of mutations are (1) spontaneous mutations (molecular decay), (2) mutations due to error-prone replication bypass of naturally occurring DNA damage (also called error-prone translesion synthesis), (3) errors introduced during DNA repair, and (4) induced mutations caused by mutagens.

What can mutations cause? ›

Genetic mutations are changes to your DNA sequence that happen during cell division when your cells make copies of themselves. Your DNA tells your body how to form and function. Genetic mutations could lead to genetic conditions like cancer, or they could help humans better adapt to their environment over time.

What are two common mutations? ›

Germ-line mutations occur in reproductive cells (sperm or eggs) and are passed to an organism's offspring during sexual reproduction. Somatic mutations occur in non-reproductive cells; they are passed to daughter cells during mitosis but not to offspring during sexual reproduction.

What are the 2 major types of mutations? ›

There are a variety of types of mutations. Two major categories of mutations are germline mutations and somatic mutations. Germline mutations occur in gametes. These mutations are especially significant because they can be transmitted to offspring and every cell in the offspring will have the mutation.

What are two real world examples of mutations? ›

For example, the yellow color on half of a petal on this red tulip was caused by a somatic mutation. The seeds of the tulip do not carry the mutation. Cancer is also caused by somatic mutations that cause a particular cell lineage (e.g., in the breast or brain) to multiply out of control.

What is the most severe mutation? ›

Frameshift mutations are generally much more serious and often more deadly than point mutations. Even though only a single nitrogen base is affected, as with point mutations, in this instance, the single base is either completely deleted or an extra one is inserted into the middle of the DNA sequence.

Is Down syndrome a mutation? ›

Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental changes and physical features of Down syndrome.

Is ADHD a genetic disorder? ›

ADHD tends to run in families and, in most cases, it's thought the genes you inherit from your parents are a significant factor in developing the condition. Research shows that parents and siblings of someone with ADHD are more likely to have ADHD themselves.

What are the 4 types of genetic variants? ›

Genetic variants are differences in DNA sequence between individuals in a population. Structural variations, single-nucleotide polymorphisms/variations (SNPs/SNVs), insertion and deletion variations, copy number variations, and translocations and inversions are the main types of variants.

What are the four classes of mutations? ›

Four classes of mutations are (1) spontaneous mutations (molecular decay), (2) mutations due to error-prone replication bypass of naturally occurring DNA damage (also called error-prone translesion synthesis), (3) errors introduced during DNA repair, and (4) induced mutations caused by mutagens.

What are the 4 types of mutations that can occur in a sequence of nucleotides? ›

Mutations can be of many types, such as substitution, deletion, insertion, and translocation.

What are the four causes of mutations? ›

Apart from mutations occurring spontaneously, certain environmental factors can cause mutations in DNA as well. Such factors or influences which permanently change the nucleotide sequence of the DNA are known as mutagens. Mutagens can be categorized into physical, chemical, and biological agents.

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